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IGHG Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IGHG in IHC (f). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6937502

Kurzübersicht für IGHG Antikörper (ABIN6937502)

Target

IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

Reaktivität

  • 14
  • 2
Human

Wirt

  • 9
  • 5
  • 2
Kaninchen

Klonalität

  • 15
  • 1
Polyklonal

Konjugat

  • 15
  • 1
Dieser IGHG Antikörper ist unkonjugiert

Applikation

  • 10
  • 10
  • 7
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Spezifität

    Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Purified human Ig Gamma Chain

    Isotyp

    IgG
  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

    Andere Bezeichnung

    IGHG

    Hintergrund

    G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4,IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)
    Cellular localisation: Cytoplasm, Cell Surface and Secreted

    Molekulargewicht

    75kDa

    Gen-ID

    3500, 3501, 3502

    UniProt

    P01857, P01859, P01860, P01861
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